Sachin Karumanchi profile photo 1 on Tal

Sachin Karumanchi

Senior AI engineer @nCodebiosciences

Andhra Pradesh

2+ years of work experience

nCode Biosciences
Jun 20266 mosPresent

Engineered a low-variance, Pareto-optimal search algorithm (Post-RL method) to optimize the design and feasibility of cell-specific mRNA. Currently leveraging Explainable AI (XAI) to discover and validate cell-specific regulatory motifs.
nCode Biosciences
Aug 20241 yr 11 mosJun 2026

On-site

Designing Generative AI architectures tailored for cell specificity. Implementing Reinforcement Learning (RL) frameworks to solve multi-objective optimization challenges—balancing complex physicochemical properties with robust cell-specific mRNA expression.
Thinkhat
Jun 20242 yrs 1 moJun 2026

Hyderabad, Telangana, India

Sachin’s AI Stack

antigravity
antigravity
claude code
claude code
claude
claude
gemini
gemini
langgraph
langgraph
notebooklm
notebooklm

Education

Indian institute of technology Hyderabad

Bachelor of Technology - BTech, Artificial Intelligence

Indian institute of technology Hyderabad

20204 yrs2024

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Headline

Senior AI engineer @nCodebiosciences

About

A graduate of the Indian Institute of Technology, Hyderabad, with a BTech in Artificial Intelligence, currently working as a Senior AI Engineer at nCode Biosciences. Brings strong expertise in Generative AI, Reinforcement Learning (RL), and Explainable AI (XAI) to drive innovation in cell-specific mRNA design. Adept in developing cutting-edge algorithms, including a low-variance, Pareto-optimal search algorithm (Post-RL method), to optimize complex biological processes. At nCode Biosciences, collaborates on leveraging XAI to identify and validate cell-specific regulatory motifs, aiming to advance the feasibility of mRNA-based solutions. Passionate about combining AI and biotechnology to address pressing challenges in precision medicine. Committed to fostering a collaborative, innovation-driven environment that bridges data science and life sciences to deliver impactful solutions.

Location

Andhra Pradesh

AI stack

antigravity

claude code

claude

gemini

langgraph

notebooklm

Work experience

Senior AI Enginner at nCode Biosciences, Jun 2026 - Present · 6 mos, Engineered a low-variance, Pareto-optimal search algorithm (Post-RL method) to optimize the design and feasibility of cell-specific mRNA. Currently leveraging Explainable AI (XAI) to discover and validate cell-specific regulatory motifs.

AI Engineer at nCode Biosciences, Aug 2024 - Jun 2026 · 1 yr 11 mos, On-site, Designing Generative AI architectures tailored for cell specificity. Implementing Reinforcement Learning (RL) frameworks to solve multi-objective optimization challenges—balancing complex physicochemical properties with robust cell-specific mRNA expression.

Associate at Thinkhat, Jun 2024 - Jun 2026 · 2 yrs 1 mo, Hyderabad, Telangana, India

Education

Bachelor of Technology - BTech, Artificial Intelligence, Indian institute of technology Hyderabad

Sachin Karumanchi - Senior AI Enginner in Andhra Pradesh | Tal