---
title: "Pratiksha Adagale - Bioinformatics AI Intern in Pimpri Chinchwad | Tal"
description: "Meet Pratiksha Adagale, Bioinformatics | Genomics | NGS | WGS | RNA-Seq | MD Simulations| Python | R programming | Linux | Nanopore Sequencing | AI/ML | Workflow Automation | Database Development based in Pimpri Chinchwad."
image: "https://tal.club/meet/pratiksha-adagale/share-image"
---

# Pratiksha Adagale on Tal

## Headline

Bioinformatics \| Genomics \| NGS \| WGS \| RNA\-Seq \| MD Simulations\| Python \| R programming \| Linux \| Nanopore Sequencing \| AI/ML \| Workflow Automation \| Database Development

## About

I am an M\.Sc\. Bioinformatics graduate with hands\-on experience in genomics, transcriptomics, AI/ML\-driven healthcare analytics, and computational biology\. • Currently Working on methylation\-based personalized medicine and Nanopore cancer genomics projects involving variant analysis, healthcare analytics dashboards, AI/ML disease prediction models, and molecular dynamics simulation\. • Performed single\-cell RNA\-seq analysis of colorectal cancer datasets to investigate tumor\-associated macrophage heterogeneity, differential gene expression, and immune\-related pathway enrichment\. • Conducted bacterial whole genome sequencing analysis using Oxford Nanopore data for genome assembly, functional annotation, and identification of abiotic stress tolerance genes\. Technical skills: • Python, R, Linux, Bash • Nanopore Sequencing, Variant Calling, scRNA\-seq • Seurat, Minimap2, Samtools, BCFtools, SnpEff, IGV • Flask, MongoDB, MySQL • Scikit\-learn, SHAP, LIME • GROMACS, PyMOL • Snakemake, Nextflow, AWS, PBS\-Pro I am particularly interested in cancer genomics, AI applications in healthcare, precision medicine, transcriptomics, and bioinformatics pipeline development\. Open to opportunities in Bioinformatics, Computational Biology, Genomics, AI/ML in Healthcare, and Precision Medicine\.

## Location

Pimpri Chinchwad

## Work experience

Bioinformatics AI Intern at Bio\-Silicon Labs Vienna, EU & UP, India, Mar 2026 \- Present · 4 mos, India, • Designed automated NGS pipelines using Snakemake and Nextflow for scalable genomic data processing\. • Performed Nanopore long\-read analysis including quality control, alignment, BAM processing, variant calling, and ClinVar\-based variant validation using tools such as Minimap2, Samtools, and BCFtools\. • Developed a Flask and MongoDB\-based healthcare analytics dashboard for storage, querying, and visualization of 4,900\+ patient stroke records\. • Built REST APIs, ETL workflows, and interactive data visualizations using PyMongo, Pandas, JavaScript, and Chart\.js for clinical data analysis\. • Developed AI/ML workflows for heart disease and stroke prediction using Scikit\-learn, CatBoost, and MLPClassifier with feature engineering, SMOTE balancing, PCA/LDA, and ensemble stacking\. • Applied explainable AI techniques including SHAP and LIME, along with evaluation metrics such as ROC and precision\-recall analysis for model interpretation\. • Performed molecular dynamics simulation and trajectory analysis of protein–ligand complexes using GROMACS to evaluate molecular stability and interactions\.

Bioinformatician at CSIR\- National Chemical Laboratory, Aug 2024 \- Jul 2025 · 1 yr, Pune, Maharashtra, India, I worked on a project titled 'Bacterial Whole Genome Analysis of Serratia fonticola to Identify Drought Tolerance Genes\.' The project data was obtained using Nanopore sequencing, and I performed the analysis using the command\-line interface\. Additionally, I have written a thesis on this project\.

## Education

Msc, Bioinformatics and Computational Biology, Dr\. D\. Y\. Patil Institute of Technology, Pimpri, Pune

Bsc biotechnology, Biotechnology, Dr\. D\. Y\. Patil Institute of Technology, Pimpri, Pune

[View the original profile](https://tal.club/meet/pratiksha-adagale)

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